Palazzo Zaccaria Pallavicino, built at the end of the 18th century at the behest of Marquis Giuseppe Maria Zaccaria, stands on the site previously occupied by Palazzo Crivelli. It is the result of the union of individual buildings of different sizes and is richly decorated by artists of the calibre of Giuseppe Natali, Sebastiano Galeotti and Giovanni Angelo Borroni.

The design of the new building is by Faustino Rodi, who was succeeded by Luigi Voghera after the death of Marquis Zaccaria and the transfer of ownership to the Pallavicino family. Voghera's contribution is particularly evident in the design of the majestic three-flight barrel-vaulted staircase, whose walls are painted to simulate the granite rustication of the exterior façade. 

Inside, the current appearance of the reception rooms on the main floor dates back to the work carried out by Renzo Mongiardino between the late 1950s and early 1960s, commissioned by the new owners, Giovanni Carotti and Andreina Negroni.